Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.52 |
| ▸ | PPARA | Q07869 | 18/20 | 0.52 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808382 | 0.92 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL4809754 | 0.88 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4810230 | 0.87 | PPARD (0.51) | PPARDPPARAPPARGMAPT | |
| SCHEMBL4808451 | 0.87 | PPARA (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4803137 | 0.86 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4808273 | 0.85 | PPARD (0.51) | PPARDPPARAPPARGALDH1A1CYP3A4 | |
| SCHEMBL4808817 | 0.85 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL4802290 | 0.84 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL4812093 | 0.84 | PPARA (0.49) | PPARDPPARAPPARG | |
| SCHEMBL4810762 | 0.83 | PPARA (0.61) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349843-B1 | THIAZOLE AND OXAZOLE DERIVATIVES AS ACTIVATORS OF HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | SMITHKLINE BEECHAM CORP (US) | 2005-04-20 | — | — | EP | claimed |