Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000880 | 1.00 | PTGER4 (0.34) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000888 | 1.00 | PTGER4 (0.34) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999495 | 0.89 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999488 | 0.89 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999449 | 0.88 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5999441 | 0.88 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000899 | 0.88 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6000890 | 0.88 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001146 | 0.86 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL6001143 | 0.86 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513523-A1 | 1,5-DISUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE AND BONE DISEASES | Merck Frosst Canada & Co. (CA) | 2005-03-16 | — | — | EP | claimed |
| WO-2003103664-A1 | 1,5-DISUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE AND BONE DISEASES | MERCK FROSST CANADA & CO. (CA) | 2003-12-18 | — | — | WO | claimed |