Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716257 | 0.85 | HTR1D (0.51) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL1545577 | 0.84 | HTR1D (0.53) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL1545159 | 0.83 | HTR1D (0.52) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7718357 | 0.83 | HTR1D (0.52) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL29282226 | 0.82 | HTR1D (0.56) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL29282221 | 0.82 | HTR1D (0.56) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL1545221 | 0.81 | HTR1D (0.51) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL9117307 | 0.80 | HTR1D (0.50) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7726678 | 0.80 | HTR1D (0.50) | HTR1DHTR1BACHEDRD2SLC6A4 | |
| SCHEMBL1545312 | 0.80 | HTR1D (0.50) | HTR1DHTR1BACHEDRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275641-B1 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-01-12 | — | — | EP | disclosed |
| US-6541471-B1 | Useful as a TXA2 receptor antagonist and a 5-HT2 receptor antagonist | LES LABORATOIRES SERVIER (FR) | 2003-04-01 | — | — | US | disclosed |
| EP-1275641-A2 | Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-01-15 | — | — | EP | disclosed |