Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6188923 | 0.90 | HTR2A (0.51) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6189799 | 0.89 | HTR2A (0.50) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6186863 | 0.88 | HTR2A (0.52) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL6190308 | 0.86 | HTR2A (0.48) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL6190410 | 0.86 | IDO1 (0.48) | HTR2AHTR1ATMEM97HTR2CDRD2 | |
| SCHEMBL6189957 | 0.86 | HTR2A (0.48) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6193126 | 0.85 | HTR2A (0.47) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6186365 | 0.85 | HTR2A (0.47) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6190906 | 0.85 | HTR2A (0.47) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL6193014 | 0.85 | IDO1 (0.48) | HTR2AHTR1ATMEM97HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |