Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181189 | 0.91 | NPC1 (0.35) | DHODHSMYD3SMN1; SMN2PDE2ALMNA | |
| SCHEMBL6182249 | 0.84 | DHODH (0.34) | DHODHSMYD3PDE2ANAMPT | |
| SCHEMBL6183081 | 0.81 | DHODH (0.34) | DHODHACACBSMN1; SMN2PDE2AMAPT | |
| SCHEMBL7924451 | 0.80 | DHODH (0.34) | DHODHSMYD3GAAPDE2ALMNA | |
| SCHEMBL8491101 | 0.80 | DHODH (0.37) | DHODHPDE2ANAMPT | |
| SCHEMBL6182710 | 0.79 | PDE2A (0.33) | DHODHACACBPDE2ALMNAPKM | |
| SCHEMBL9115094 | 0.79 | DHODH (0.34) | DHODHSMYD3GAAPDE2ALMNA | |
| SCHEMBL8488330 | 0.79 | PDE2A (0.36) | DHODHSMN1; SMN2PDE2ALMNAMAPT | |
| SCHEMBL8494964 | 0.78 | DHODH (0.33) | DHODHSMYD3PDE2ANAMPT | |
| SCHEMBL9116308 | 0.78 | DHODH (0.33) | DHODHSMYD3PDE2ALMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| CN-1039904-C | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-09-23 | — | — | CN | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| CN-1104212-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-28 | — | — | CN | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |