Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 13/20 | 0.78 |
| ▸ | MAP2K1 | Q02750 | 9/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAP3K1 | Q13233 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183822 | 0.89 | IGF1R (0.76) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL6182651 | 0.88 | IGF1R (1.00) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL6183047 | 0.85 | IGF1R (0.66) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL7000398 | 0.84 | IGF1R (0.75) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL5255712 | 0.81 | IGF1R (0.68) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL5255981 | 0.81 | IGF1R (0.65) | IGF1RMAP2K1MAPK3MAPK1MAP3K1 | |
| SCHEMBL7001176 | 0.80 | MAP2K1 (0.77) | IGF1RMAP2K1EGFRMAPK3MAPK1 | |
| SCHEMBL7001879 | 0.80 | MAP2K1 (0.63) | IGF1RMAP2K1MAPK3MAPK1MAP3K1 | |
| SCHEMBL6181198 | 0.80 | IGF1R (1.00) | IGF1RMAP2K1EGFRERBB2MAPK3 | |
| SCHEMBL5255721 | 0.79 | IGF1R (0.65) | IGF1RMAP2K1EGFRERBB2MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499594-B1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH CORP (US) | 2005-08-17 | — | — | EP | claimed |