SCHEMBL6187592

SCHEMBL6187592

CN(Cc1cccc(-c2ccc(CC3SC(=O)NC3=O)cc2)c1)C(=O)c1ccc(CC(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.53
HSD17B2 P37059 6/20 0.50
HSD17B1 P14061 4/20 0.50
PPARG P37231 4/20 0.46
AOC3 Q16853 6/20 0.44
MPC2 O95563 1/20 0.42
CYP2C8 P10632 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399098 0.94 FFAR1 (0.59) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL5760451 0.93 FFAR1 (0.55) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6184172 0.92 FFAR1 (0.59) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL5403696 0.91 FFAR1 (0.56) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6182440 0.91 HSD17B2 (0.57) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6183498 0.91 HSD17B2 (0.53) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL5399315 0.91 HSD17B2 (0.57) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6185090 0.90 FFAR1 (0.52) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6181638 0.90 FFAR1 (0.52) FFAR1HSD17B2HSD17B1PPARGAOC3
SCHEMBL6183571 0.89 FFAR1 (0.51) FFAR1HSD17B2HSD17B1PPARGAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309575-B1 BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS GALDERMA RES & DEV (FR) 2005-06-08 EP claimed