⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277544 | 0.74 | — | — | |
| SCHEMBL108283 | 0.74 | — | — | |
| SCHEMBL8277451 | 0.74 | — | — | |
| SCHEMBL361589 | 0.74 | — | — | |
| SCHEMBL185354 | 0.74 | — | — | |
| SCHEMBL16158874 | 0.74 | — | — | |
| SCHEMBL1336542 | 0.74 | — | — | |
| SCHEMBL10044966 | 0.72 | RNPEP (0.39) | — | |
| Hydrochloric Acid SCHEMBL3345131 | 0.72 | RNPEP (0.50) | — | |
| SCHEMBL6269846 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554250-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031154-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-04-15 | — | — | WO | disclosed |