Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190964 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1PKMTSHRKDM4E | |
| SCHEMBL6192322 | 0.89 | CNR2 (0.38) | NPSR1ALDH1A1KDM4EHPGDCNR2 | |
| SCHEMBL6189905 | 0.89 | NPC1 (0.43) | NPSR1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6189898 | 0.89 | NPC1 (0.43) | NPSR1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6192319 | 0.89 | CNR2 (0.38) | NPSR1ALDH1A1KDM4EHPGDCNR2 | |
| SCHEMBL6188288 | 0.89 | CNR2 (0.43) | CNR2CNR1KCNQ3KCNQ2 | |
| SCHEMBL6188291 | 0.89 | CNR2 (0.43) | CNR2CNR1KCNQ3KCNQ2 | |
| SCHEMBL6187172 | 0.87 | CNR2 (0.40) | NPSR1ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6187170 | 0.87 | CNR2 (0.40) | NPSR1ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL6191362 | 0.87 | KCNQ3 (0.46) | KDM4EHPGDPOLBTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043319-B1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1043319-A1 | NOVEL ALKYLAMINO DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |