SCHEMBL6191995

SCHEMBL6191995

Cc1oc(CCC(=O)c2ccccc2S(N)(=O)=O)cc1COc1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3543205 0.81 PTGER4 (1.00) PTGER4
SCHEMBL3538559 0.77 PTGER4 (0.70) PTGER4
SCHEMBL3536569 0.76 PTGER4 (0.84) PTGER4
SCHEMBL3533433 0.75 PTGER4 (1.00) PTGER4
SCHEMBL3536863 0.75 PTGER4 (0.65) PTGER4
SCHEMBL3532981 0.75 PTGER4 (0.70) PTGER4
SCHEMBL3537522 0.70 PTGER4 (0.65) PTGER4
SCHEMBL1756460 0.70 PTGER4 (1.00) PTGER4
SCHEMBL3536921 0.69 PTGER4 (0.84) PTGER4
SCHEMBL4693788 0.69 PTGER4 (0.70) PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603893-A1 EP4 RECEPTOR ANTAGONISTS Pharmagene Laboratories Ltd (GB) 2005-12-14 EP disclosed
WO-2004067524-A1 EP4 RECEPTOR ANTAGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2004-08-12 WO disclosed