Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 8/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 14/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105940 | 0.87 | AVPR2 (0.47) | AVPR1AAVPR2 | |
| SCHEMBL6210294 | 0.85 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL5108897 | 0.83 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL5106699 | 0.82 | AVPR2 (0.49) | AVPR1AAVPR2 | |
| SCHEMBL5117312 | 0.81 | AVPR1A (0.60) | AVPR1AAVPR2 | |
| SCHEMBL6190961 | 0.80 | AVPR2 (0.40) | AVPR1AAVPR2 | |
| SCHEMBL6475869 | 0.79 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL6476096 | 0.79 | AVPR1A (0.41) | AVPR1AAVPR2 | |
| SCHEMBL6476800 | 0.78 | AVPR2 (0.44) | AVPR1AAVPR2 | |
| SCHEMBL6190069 | 0.78 | AVPR1A (0.49) | AVPR1AAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377585-B1 | NOVEL 10-CYCLOHEXENYL-PHENYL PYRROLOBENZODIAZEPINE-3-CARBOXAMIDES AND DERIVATIVES THEREOF; TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | WYETH CORP (US) | 2005-11-09 | — | — | EP | claimed |