Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963869 | 0.87 | CNR2 (1.00) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5963872 | 0.87 | CNR2 (1.00) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5964304 | 0.87 | CNR2 (1.00) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6192436 | 0.83 | CNR2 (0.72) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5964161 | 0.83 | CNR2 (0.72) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5964266 | 0.82 | CNR2 (0.71) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5964005 | 0.81 | CNR2 (0.57) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6212084 | 0.81 | MEN1 (0.59) | CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL5964676 | 0.78 | CNR2 (0.83) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5964068 | 0.77 | CNR2 (0.67) | CNR2KDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594856-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2005-11-16 | — | — | EP | claimed |
| WO-2004060882-A1 | CB 1/CB 2 RECEPTOR LIGANDS AND THEIR USE IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2004-07-22 | — | — | WO | claimed |