SCHEMBL6196448

SCHEMBL6196448

CN[C]NC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27208490 0.62
SCHEMBL913694 0.62
SCHEMBL386866 0.59
SCHEMBL1013709 0.59
SCHEMBL387801 0.59
SCHEMBL5670 0.59
SCHEMBL6256554 0.59
SCHEMBL207092 0.59
SCHEMBL208927 0.59
SCHEMBL300977 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878701-B2 Potassium channel blocking agents NEUROSEARCH A/S (DK) 2005-04-12 US claimed
EP-1091942-B1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH AS (DK) 2005-03-30 EP claimed
EP-1196419-B1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH AS (DK) 2003-09-24 EP claimed
US-20020137784-A1 Potassium channel blocking agents NEUROSEARCH A/S 2002-09-26 US claimed
US-20020128279-A1 Potassium channel blocking agents NEUROSEARCH A/S (DK) 2002-09-12 US claimed
US-6380180-B1 BENZIMIDAZOLE COMPOUNDS FOR TREATMENT OF ASTHMA, VASOSPASM, MEMORY LOSS, MIGRAINE AND OTHERS DISEASES ASSOCIATED WITH POTASSIUM CHANNELS NEUROSEARCH A/S (DK) 2002-04-30 US claimed
US-20020049246-A1 Potassium channel blocking agents NEUROSEARCH A/S 2002-04-25 US claimed
EP-1196419-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2002-04-17 EP claimed
EP-1091942-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2001-04-18 EP claimed
US-6194447-B1 ASTHMA, ANTICONVULSANTS, COGNITION ACTIVATORS, BRAIN DISORDERS, PSYCHOLOGICAL DISORDERS, CARDIOVASCULAR DISORDERS,GASTROINTESTINAL DISORDERS NEUROSEARCH A/S (DK) 2001-02-27 US claimed
WO-2001002406-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2001-01-11 WO claimed
WO-2000001676-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2000-01-13 WO claimed
US-6878701-B2 Potassium channel blocking agents NEUROSEARCH A/S (DK) 2005-04-12 US disclosed
EP-1091942-B1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH AS (DK) 2005-03-30 EP disclosed
EP-1196419-B1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH AS (DK) 2003-09-24 EP disclosed
US-6569880-B2 Guanidine derivatives NEUROSEARCH A/S (DK) 2003-05-27 US disclosed
US-6380180-B1 BENZIMIDAZOLE COMPOUNDS FOR TREATMENT OF ASTHMA, VASOSPASM, MEMORY LOSS, MIGRAINE AND OTHERS DISEASES ASSOCIATED WITH POTASSIUM CHANNELS NEUROSEARCH A/S (DK) 2002-04-30 US disclosed
EP-1196419-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2002-04-17 EP disclosed
US-6194447-B1 ASTHMA, ANTICONVULSANTS, COGNITION ACTIVATORS, BRAIN DISORDERS, PSYCHOLOGICAL DISORDERS, CARDIOVASCULAR DISORDERS,GASTROINTESTINAL DISORDERS NEUROSEARCH A/S (DK) 2001-02-27 US disclosed
WO-2001002406-A1 POTASSIUM CHANNEL BLOCKING AGENTS NEUROSEARCH A/S (DK) 2001-01-11 WO disclosed