Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14251166 | 0.86 | KCNA3 (0.61) | KCNA3MAPTCACNA2D1MAPK1 | |
| SCHEMBL11713358 | 0.83 | KCNA3 (0.47) | KCNA3TNFMAPTCACNA2D1 | |
| SCHEMBL28985974 | 0.80 | HTR1B (0.65) | KCNA3TNFMAPTCACNA2D1 | |
| SCHEMBL14603570 | 0.80 | TNF (0.56) | KCNA3TNFMAPTCACNA2D1 | |
| SCHEMBL1759351 | 0.80 | MCHR1 (0.51) | KCNA3TNFMAPT | |
| SCHEMBL21266927 | 0.79 | IKBKB (0.50) | KCNA3TNFMAPTMAPK1 | |
| SCHEMBL1660061 | 0.78 | KCNA3 (0.56) | KCNA3TNFMAPT | |
| SCHEMBL7053152 | 0.77 | HTR1B (0.60) | KCNA3 | |
| SCHEMBL23544069 | 0.77 | TNF (0.49) | KCNA3TNFMAPTCACNA2D1 | |
| SCHEMBL1491286 | 0.77 | MAPT (0.56) | TNFMAPTCACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583537-A3 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-12-14 | — | — | EP | disclosed |
| EP-1583537-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2005-10-12 | — | — | EP | disclosed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
| WO-2004002490-A2 | PIPERIDINE COMPOUNDS AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |