Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 11/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557972 | 0.86 | CCR3 (0.65) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL4861307 | 0.84 | CCR3 (0.62) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL6198672 | 0.83 | CCR3 (0.62) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL4862935 | 0.81 | CCR3 (0.59) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL6195675 | 0.81 | CCR3 (0.60) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL6195682 | 0.80 | CCR3 (0.57) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL6195652 | 0.79 | CCR3 (0.56) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL3557299 | 0.79 | CCR3 (0.67) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL27612470 | 0.77 | CCR3 (0.56) | CCR3HTR2AMEN1POLBKMT2A | |
| SCHEMBL3568569 | 0.77 | CCR3 (0.64) | CCR3HTR2AMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499607-B1 | 4-(PIPERIDYL- AND PYRROLIDYL-ALKYL-UREIDO)-QUINOLINES AS UROTENSIN II RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2005-12-07 | — | — | EP | disclosed |