Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.60 |
| ▸ | KLK7 | P49862 | 2/20 | 0.57 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 2/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.54 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328141 | 0.94 | SIRT2 (0.66) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL5328146 | 0.94 | SIRT2 (0.66) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL699636 | 0.93 | FOLH1 (0.65) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL1491720 | 0.93 | FOLH1 (0.65) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL2467817 | 0.93 | FOLH1 (0.65) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL29119131 | 0.90 | SIRT2 (0.59) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL29119136 | 0.90 | SIRT2 (0.59) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL1021938 | 0.90 | SYK (0.60) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL918813 | 0.90 | SYK (0.60) | SIRT2SIRT1FOLH1KLK7KLK5 | |
| SCHEMBL4958981 | 0.90 | SYK (0.60) | SIRT2SIRT1FOLH1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |