Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199674 | 1.00 | CETP (0.54) | CETP | |
| SCHEMBL6398393 | 0.92 | CETP (0.64) | CETP | |
| SCHEMBL1242569 | 0.92 | CETP (0.64) | CETP | |
| SCHEMBL992496 | 0.92 | CETP (0.64) | CETP | |
| SCHEMBL6588165 | 0.89 | CETP (0.63) | CETP | |
| SCHEMBL6588803 | 0.89 | CETP (0.63) | CETP | |
| SCHEMBL6198972 | 0.88 | CETP (0.53) | CETP | |
| SCHEMBL6198969 | 0.88 | CETP (0.53) | CETP | |
| SCHEMBL6588964 | 0.88 | CETP (0.53) | CETP | |
| SCHEMBL6588960 | 0.88 | CETP (0.53) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992496-B1 | Annulated 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as CETP inhibitors | PFIZER PROD INC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-6147089-A | CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS USED TO TREAT DISEASES WHICH ARE EXACERBATED BY LOW LEVELS OF HDL CHOLESTEROL AND/OR HIGH LEVELS OF LDL-CHOLESTEROL AND TRIGLYCERIDES, SUCH AS ATHEROSCLEROSIS AND CARDIOVASCULAR | PFIZER INC. (US) | 2000-11-14 | — | — | US | disclosed |
| EP-0992496-A1 | Annulated 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as CETP inhibitors | Pfizer Products Inc. (US) | 2000-04-12 | — | — | EP | disclosed |