Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200734 | 0.87 | EGLN1 (0.47) | EGLN1CNR2NR3C1HPGDLMNA | |
| SCHEMBL6198898 | 0.86 | EGLN1 (0.44) | EGLN1CNR2NR3C1HTTMAPT | |
| SCHEMBL6199704 | 0.85 | EGLN1 (0.49) | EGLN1CNR2HTTKDM4ELMNA | |
| SCHEMBL6198169 | 0.83 | EGLN1 (0.49) | EGLN1CNR2NR3C1HTTKDM4E | |
| SCHEMBL6197374 | 0.83 | EGLN1 (0.41) | EGLN1CNR2NR3C1MAPTHPGD | |
| SCHEMBL6199941 | 0.83 | MEN1 (0.49) | EGLN1CNR2MAPTKDM4EALDH1A1 | |
| SCHEMBL6201600 | 0.81 | EGLN1 (0.47) | EGLN1CNR2NR3C1HPGDLMNA | |
| SCHEMBL6201102 | 0.81 | EGLN1 (0.47) | EGLN1CNR2NR3C1HPGDLMNA | |
| SCHEMBL6202614 | 0.81 | EGLN1 (0.47) | EGLN1CNR2NR3C1HPGDLMNA | |
| SCHEMBL6219084 | 0.81 | EGLN1 (0.54) | EGLN1NR3C1HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |