Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9731174 | 0.80 | NQO2 (0.47) | NQO2TRPM4ERN1KDM4ECYP1A2 | |
| SCHEMBL11963905 | 0.80 | NQO2 (0.55) | NQO2TRPM4ERN1KDM4ECYP1A2 | |
| SCHEMBL9731171 | 0.79 | EGFR (0.56) | NQO2TRPM4ERN1KDM4EPTGS2 | |
| SCHEMBL9098185 | 0.78 | PLAU (0.53) | KDM4EPTGS2RAB9ACYP1A2ALDH1A1 | |
| SCHEMBL17058718 | 0.78 | ESR1 (0.48) | ERN1KDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL2996328 | 0.78 | ERN1 (0.45) | ERN1KDM4ERAB9ACYP1A2PTPN1 | |
| SCHEMBL6362144 | 0.78 | CYP1A2 (0.57) | ERN1KDM4EPTGS2RAB9ACYP1A2 | |
| SCHEMBL31141573 | 0.78 | ERN1 (0.45) | ERN1KDM4ERAB9ACYP1A2PTPN1 | |
| SCHEMBL29951294 | 0.78 | CYP1A2 (0.57) | ERN1KDM4EPTGS2RAB9ACYP1A2 | |
| SCHEMBL17988314 | 0.77 | KDM4E (0.56) | NQO2TRPM4KDM4ERAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118731194-A | Detection method of alkyl diamine | 四川科伦药物研究院有限公司 | 2024-10-01 | — | — | CN | claimed |
| WO-2025033019-A1 | COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND PRODUCTION METHOD | 三菱瓦斯化学株式会社 | 2025-02-13 | — | — | WO | disclosed |
| WO-2024214321-A1 | COMPOUND, COMPOSITION, METHOD FOR EXPRESSING SENSITIZING EFFECT, AND METHOD FOR PRODUCING SAME | 三菱瓦斯化学株式会社 | 2024-10-17 | — | — | WO | disclosed |
| CN-118731194-A | Detection method of alkyl diamine | 四川科伦药物研究院有限公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20240270758-A1 | PYRIDINO-OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | ZHEJIANG GENFLEET THERAPEUTICS CO., LTD. (CN) | 2024-08-15 | — | — | US | disclosed |
| EP-4332105-A1 | PYRIDINO- OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-03-06 | — | — | EP | disclosed |
| CN-117222650-A | Pyridine or pyrimido-ring compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2022228568-A1 | PYRIDINO- OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-11-03 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-104470985-B | The manufacture method of polymer composition and polymer composition | BRIDGESTONE CO.,LTD. (JP) | 2016-05-18 | — | — | CN | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4992514-A | From mixtures of polyamide and thermotropic liquid crystalline polymer by deforming preform above polyamide glass transition temperature | EMS-INVENTA AG (CH) | 1991-02-12 | — | — | US | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4933399-A | COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| CN-1035118-A | A kind of method that forms polymer-scale that stops | SHINETSU CHEMICAL CO (JP) | 1989-08-30 | — | — | CN | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0320227-A2 | Method of preventing polymer-scale formation | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270758-A1 | PYRIDINO-OR PYRIMIDO-CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | KRAS, NRAS, BRAF | NQO2 696/4885TRPM4 3811/4885ERN1 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.