SCHEMBL6200743

SCHEMBL6200743

Cn1ncc(Br)c1-c1cccc(NC(=O)Nc2cc(F)cc(F)c2)c1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 19/20 0.72
HTR2C P28335 17/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6199703 0.88 HTR2A (0.78) HTR2AHTR2C
SCHEMBL6195174 0.86 HTR2A (0.60) HTR2AHTR2C
SCHEMBL6197718 0.86 HTR2A (0.69) HTR2AHTR2C
SCHEMBL6198042 0.85 HTR2A (0.64) HTR2AHTR2C
SCHEMBL6198081 0.85 HTR2A (0.80) HTR2AHTR2C
SCHEMBL5946822 0.84 HTR2A (0.54) HTR2AHTR2C
SCHEMBL6194881 0.84 HTR2A (0.77) HTR2AHTR2C
SCHEMBL6201624 0.84 HTR2A (1.00) HTR2AHTR2C
SCHEMBL6201230 0.84 HTR2A (0.61) HTR2AHTR2C
SCHEMBL6196466 0.84 HTR2A (0.69) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1509505-A2 SMALL MOLECULE MODULATORS OF THE 5−HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2005-03-02 EP claimed
WO-2003062206-A2 SMALL MOLECULE MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2003-07-31 WO claimed