Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287393 | 0.76 | TSHR (0.36) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL16382875 | 0.74 | TSHR (0.40) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL6937150 | 0.74 | TSHR (0.40) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| Hydrochloric Acid SCHEMBL11280986 | 0.74 | TSHR (0.35) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL83786 | 0.72 | TSHR (0.55) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL18970410 | 0.72 | KDM4E (0.42) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL16675272 | 0.72 | TSHR (0.38) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL85493 | 0.71 | TSHR (0.57) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL791722 | 0.71 | — | — | |
| SCHEMBL314782 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790721-B | Synthetic method of ceftazidime side chain ethyl ester | 山东金城医药化工有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-108576835-B | Juicing device used in fruit and vegetable processing and working method thereof | 徐州工程学院 | 2021-03-19 | — | — | CN | claimed |
| CN-115353581-A | Coating agent in charged cleaning agent for network communication equipment and preparation method | 天津维诺嘉华科技有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-113336678-B | Electron-rich condensed ring aryl nitrone fluorescent probe and preparation and application thereof | 华中科技大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-110790721-B | Synthetic method of ceftazidime side chain ethyl ester | 山东金城医药化工有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113372292-A | Preparation method of ceftazidime side chain acid | 山东昌邑四方医药化工有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-110143902-B | Selenium-containing chalcone derivative Compound1, synthesis method and application in non-alcoholic steatohepatitis resisting medicine | 天津科技大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-108576835-B | Juicing device used in fruit and vegetable processing and working method thereof | 徐州工程学院 | 2021-03-19 | — | — | CN | disclosed |
| CN-110143890-B | Chalcone derivative, synthesis method and application of chalcone derivative in preparation of non-alcoholic steatohepatitis resistant medicine | 天津科技大学 | 2020-12-22 | — | — | CN | disclosed |
| EP-1372656-B1 | PYRAZOLO[4,3-D]PYRIMIDINONE COMPOUNDS AS CGMP PDE INHIBITORS | PFIZER LTD (GB) | 2005-06-22 | — | — | EP | disclosed |
| US-6784185-B2 | PYRAZOLO(4,3-D) PYRIMIDINONE COMPOUNDS USEFUL AS CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASES (CGMP PDES) INHIBITOR | PFIZER INC. | 2004-08-31 | — | — | US | disclosed |
| US-20020198223-A1 | Pharmaceutically active compounds | PFIZER INC. | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198223-A1 | Pharmaceutically active compounds | PDE5A, PDE3A, PDE2A | TSHR 2852/4885ALDH1A1 298/4885CYP2D6 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.