Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202810 | 0.95 | SIRT2 (0.53) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL29387849 | 0.93 | KLK7 (0.54) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL29942889 | 0.92 | KLK7 (0.53) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL20529968 | 0.92 | KLK7 (0.53) | KLK7KLK5MAPTTLR2TLR1 | |
| SCHEMBL29521232 | 0.92 | KLK7 (0.54) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL30266749 | 0.92 | KLK7 (0.51) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL28434464 | 0.92 | KLK7 (0.51) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL30266783 | 0.92 | KLK7 (0.51) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL28443557 | 0.92 | KLK7 (0.51) | KLK7KLK5MAPTHDAC1HDAC2 | |
| SCHEMBL30266828 | 0.92 | KLK7 (0.51) | KLK7KLK5MAPTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1165532-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058294-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |