Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647680 | 1.00 | DPP4 (0.61) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL645893 | 1.00 | DPP4 (0.61) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL4702439 | 1.00 | DPP4 (0.61) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL4704014 | 1.00 | DPP4 (0.61) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL4704016 | 1.00 | DPP4 (0.61) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL648116 | 0.87 | DPP4 (0.62) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL647636 | 0.87 | DPP4 (0.62) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL650946 | 0.87 | DPP4 (0.58) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL646035 | 0.87 | DPP4 (0.58) | DPP4DPP9EPHX2DPP8 | |
| SCHEMBL6508986 | 0.84 | DPP4 (0.68) | DPP4DPP9EPHX2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |