Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809668 | 0.88 | DRD3 (0.63) | KMT2AMEN1DRD3HPGDLMNA | |
| SCHEMBL29548224 | 0.88 | DRD3 (0.63) | KMT2AMEN1DRD3HPGDLMNA | |
| SCHEMBL8500940 | 0.88 | KMT2A (0.52) | KMT2AGAAMEN1RAD52DRD3 | |
| SCHEMBL541724 | 0.87 | DRD3 (0.61) | KMT2AMEN1DRD3HPGDLMNA | |
| Hydrochloric Acid SCHEMBL28333431 | 0.87 | DRD3 (0.61) | KMT2AMEN1DRD3HPGDLMNA | |
| SCHEMBL541723 | 0.87 | DRD3 (0.61) | KMT2AMEN1DRD3HPGDLMNA | |
| Fluoride SCHEMBL6764129 | 0.86 | DRD3 (0.60) | KMT2AMEN1DRD3HPGDLMNA | |
| SCHEMBL10472032 | 0.85 | POLB (0.55) | KMT2AGAAMEN1RAD52DRD3 | |
| SCHEMBL6764138 | 0.85 | DRD3 (0.59) | KMT2AMEN1DRD3HPGDLMNA | |
| SCHEMBL29823822 | 0.84 | POLB (0.69) | KMT2AMEN1DRD3HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |