Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.59 |
| ▸ | PPARA | Q07869 | 15/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028338 | 0.93 | PPARG (0.59) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL6201108 | 0.89 | PPARG (0.60) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL6203280 | 0.89 | FFAR1 (0.58) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL4028563 | 0.86 | FFAR1 (0.60) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL13633933 | 0.86 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL4025975 | 0.85 | FFAR1 (0.58) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL6204434 | 0.83 | FFAR1 (0.59) | PPARGPPARAFFAR1PPARD | |
| SCHEMBL4026910 | 0.82 | FFAR1 (0.63) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL4027559 | 0.82 | FFAR1 (0.60) | PPARGPPARAFFAR1PPARDKDR | |
| SCHEMBL4029576 | 0.81 | FFAR1 (0.58) | PPARGPPARAFFAR1PPARDKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD. (IN) | 2005-09-07 | — | — | EP | claimed |
| WO-2004046119-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| EP-1569916-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD. (IN) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046119-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |