Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197994 | 0.87 | KMT2A (0.54) | PPARAEGLN1KMT2ANR3C1ALDH1A1 | |
| SCHEMBL6195970 | 0.84 | EGLN1 (0.46) | PPARAEGLN1KMT2AMEN1NR3C1 | |
| SCHEMBL6195978 | 0.84 | KMT2A (0.47) | PPARAEGLN1KMT2AMEN1NR3C1 | |
| SCHEMBL6197307 | 0.83 | EGLN1 (0.44) | PPARAEGLN1KMT2AMEN1NR3C1 | |
| SCHEMBL6196427 | 0.82 | SMN1; SMN2 (0.49) | PPARAEGLN1KMT2ANR3C1SMN1; SMN2 | |
| SCHEMBL6199108 | 0.82 | KMT2A (0.47) | PPARAEGLN1KMT2ANR3C1SMN1; SMN2 | |
| SCHEMBL6199879 | 0.82 | KMT2A (0.46) | PPARAEGLN1KMT2ANR3C1SMN1; SMN2 | |
| SCHEMBL6200663 | 0.81 | CSF1R (0.53) | PPARAKMT2ANR3C1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6198708 | 0.81 | EGLN1 (0.44) | PPARAEGLN1KMT2AMEN1NR3C1 | |
| SCHEMBL6201385 | 0.80 | EGLN1 (0.52) | EGLN1NR3C1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |