Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 15/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 15/20 | 1.00 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819402 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2819389 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2820608 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2820120 | 0.92 | CHRM3 (0.85) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2823076 | 0.87 | CHRM3 (0.77) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL4542752 | 0.85 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2820947 | 0.85 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2819392 | 0.85 | CHRM3 (1.00) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL2819039 | 0.82 | CHRM3 (0.76) | CHRM3CHRM2CHRM1HTR3EHTR3B | |
| SCHEMBL4922233 | 0.82 | CHRM3 (0.76) | CHRM3CHRM2CHRM1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005533826-A | — | — | 2005-11-10 | — | — | JP | claimed |
| EP-1519933-A1 | QUINUCLIDINE AMIDE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2005-04-06 | — | — | EP | claimed |
| WO-2004005285-A1 | NEW QUINUCLIDINE AMIDE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-01-15 | — | — | WO | claimed |
| EP-1519933-A1 | QUINUCLIDINE AMIDE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005285-A1 | NEW QUINUCLIDINE AMIDE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-01-15 | — | — | WO | disclosed |