Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.55 |
| ▸ | HTR2C | P28335 | 16/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197871 | 0.92 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL6198353 | 0.91 | HTR2A (0.56) | HTR2AHTR2CIDO1 | |
| SCHEMBL6199690 | 0.89 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL6198521 | 0.89 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL6197320 | 0.87 | HTR2A (0.69) | HTR2AHTR2C | |
| SCHEMBL6200146 | 0.86 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL6201174 | 0.86 | HTR2A (0.56) | HTR2AHTR2C | |
| SCHEMBL6201315 | 0.85 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL6197166 | 0.85 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL6200476 | 0.85 | HTR2A (0.63) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509505-A2 | SMALL MOLECULE MODULATORS OF THE 5−HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003062206-A2 | SMALL MOLECULE MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2003-07-31 | — | — | WO | claimed |