Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910012 | 0.91 | MEN1 (0.62) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL14601810 | 0.90 | MEN1 (0.61) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL13777298 | 0.89 | SMN1; SMN2 (0.52) | CYP4F2CYP4A11MAOBLTB4RLTB4R2 | |
| SCHEMBL3271153 | 0.88 | CYP4F2 (0.61) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL6035513 | 0.87 | MAOB (0.65) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL2938664 | 0.84 | NQO1 (0.46) | CYP4F2CYP4A11TSHRTP53PTGS2 | |
| SCHEMBL9454030 | 0.83 | GRM5 (0.54) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL2808909 | 0.83 | GPBAR1 (0.58) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL2814524 | 0.83 | MAOB (0.51) | MEN1KMT2ACYP4F2CYP4A11MAOB | |
| SCHEMBL13434095 | 0.82 | MAOB (0.73) | CYP4F2CYP4A11MAOBLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |