Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202772 | 0.85 | EGLN1 (0.50) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6199668 | 0.84 | EGLN1 (0.49) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6219084 | 0.83 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6198610 | 0.82 | EGLN1 (0.56) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6198755 | 0.82 | POLA1 (0.57) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6198193 | 0.81 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6200839 | 0.81 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6202284 | 0.81 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6198854 | 0.81 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 | |
| SCHEMBL6202038 | 0.81 | EGLN1 (0.54) | KDM4EALDH1A1HPGDEGLN1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042295-B1 | 4-HYDROXYQUINOLINE-3-CARBOXAMIDES AND HYDRAZIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-09-07 | — | — | EP | claimed |