Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084691 | 0.79 | CETP (0.59) | CETPMAPTTHRBKMT2AMEN1 | |
| SCHEMBL6201770 | 0.79 | CETP (0.51) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6084333 | 0.77 | CETP (0.56) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6085579 | 0.76 | CETP (0.52) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6085596 | 0.74 | CETP (0.48) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6085287 | 0.74 | CETP (0.56) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6086812 | 0.74 | CETP (0.50) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6085349 | 0.73 | CETP (0.53) | UTRNCYP1A2AHRHDAC6CETP | |
| SCHEMBL6085118 | 0.73 | CETP (0.51) | HDAC6CETPMAPTTHRBRXFP1 | |
| SCHEMBL6085938 | 0.73 | CETP (0.50) | UTRNCYP1A2AHRHDAC6CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |