Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.74 |
| ▸ | MAPK13 | O15264 | 19/20 | 0.74 |
| ▸ | MAPK12 | P53778 | 19/20 | 0.74 |
| ▸ | MAPK11 | Q15759 | 19/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202199 | 0.89 | MAPK13 (0.58) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6202228 | 0.88 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6202225 | 0.88 | MAPK14 (0.70) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4850746 | 0.85 | MAPK13 (1.00) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4850749 | 0.85 | MAPK13 (1.00) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6202202 | 0.85 | MAPK13 (0.58) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6203111 | 0.81 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL6203113 | 0.81 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4861369 | 0.80 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4861384 | 0.80 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427727-B1 | COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES | PROCTER & GAMBLE (US) | 2005-01-26 | — | — | EP | disclosed |
| US-6821971-B2 | FOR PROPHYALXIS OF RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, INFLAMMATORY BOWEL DISEASE (IBS), SEPTIC SHOCK, CARDIOPULMONARY DYSFUNCTION, ACUTE RESPIRATORY DISEASE, CACHEXIA | THE PROCTER & GAMBLE COMPANY | 2004-11-23 | — | — | US | disclosed |
| EP-1427727-A1 | COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES | THE PROCTER & GAMBLE COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024970-A1 | COMPOUNDS WHICH INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES | THE PROCTER & GAMBLE COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |