Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.60 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378288 | 0.84 | DPP4 (0.61) | DPP4DPP8DPP7DPP9FAP | |
| Hydrochloric Acid SCHEMBL6204799 | 0.83 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP | |
| Hydrochloric Acid SCHEMBL6204796 | 0.83 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL13034928 | 0.82 | DPP4 (0.79) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15130351 | 0.82 | DPP4 (0.79) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL8277346 | 0.79 | DPP4 (0.65) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14392392 | 0.79 | DPP4 (0.65) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14392760 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15636202 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15636200 | 0.78 | DPP4 (1.00) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |