Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.63 |
| ▸ | PPARA | Q07869 | 15/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027981 | 0.94 | PPARG (0.65) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL4027979 | 0.85 | PPARG (0.68) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL4027996 | 0.82 | PPARG (0.71) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL12442798 | 0.81 | PPARA (0.64) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6202684 | 0.81 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL4029812 | 0.81 | PPARG (0.70) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL6202354 | 0.81 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL4028994 | 0.80 | PPARA (0.61) | PPARGPPARAPPARDKDM4EMAPT | |
| SCHEMBL6228947 | 0.80 | PPARG (0.80) | PPARGPPARAPPARD | |
| SCHEMBL4029074 | 0.80 | PPARG (0.68) | PPARGPPARAPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD. (IN) | 2005-09-07 | — | — | EP | claimed |
| WO-2004046119-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2004-06-03 | — | — | WO | claimed |
| EP-1569916-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD. (IN) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004046119-A1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2004-06-03 | — | — | WO | disclosed |