Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.72 |
| ▸ | MC3R | P41968 | 1/20 | 0.72 |
| ▸ | MC1R | Q01726 | 1/20 | 0.72 |
| ▸ | AKT1 | P31749 | 7/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476507 | 1.00 | MC4R (0.72) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6197940 | 1.00 | MC4R (0.72) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6180978 | 1.00 | MC4R (0.72) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6476513 | 0.99 | MC4R (0.71) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6180966 | 0.95 | MC4R (0.65) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6488305 | 0.91 | MC4R (0.61) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6485785 | 0.91 | MC4R (0.61) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6182157 | 0.91 | MC4R (0.65) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6483088 | 0.88 | MC4R (0.57) | MC4RMC3RMC1RAKT1DPP4 | |
| SCHEMBL6197883 | 0.88 | MC4R (0.70) | MC4RMC3RMC1RAKT1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239835-A1 | Melanocortin receptor ligands | EBETINO FRANK H | 2005-10-27 | — | — | US | disclosed |
| EP-1499314-A1 | N-ACYL PIPERIDINE DERIVATIVES FOR USE AS MELANOCORTIN RECEPTOR LIGANDS IN THE TREATMENT OF FEEDING DISORDERS | The Procter & Gamble Company (US) | 2005-01-26 | — | — | EP | disclosed |
| US-20040010010-A1 | Melanocortin receptor ligands | PROCTER & GAMBLE COMPANY, THE | 2004-01-15 | — | — | US | disclosed |
| WO-2003092690-A1 | N-ACYL PIPERIDINE DERIVATIVES FOR USE AS MELANOCORTIN RECEPTOR LIGANDS IN THE TREATMENT OF FEEDING DISORDERS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239835-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC3R | MC4R 2/4885MC3R 3/4885MC1R 1/4885 |
| US-20040010010-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | MC4R 2/4885MC3R 4/4885MC1R 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.