SCHEMBL620257

SCHEMBL620257

O=[N+]([O-])C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9481202 0.81
SCHEMBL10896042 0.79
SCHEMBL30762097 0.76 TSHR (0.50)
Chloropicrin SCHEMBL75169 0.75
Chloropicrin SCHEMBL604956 0.75 TSHR (1.00)
SCHEMBL1436541 0.75
SCHEMBL29889228 0.74 TSHR (0.47)
SCHEMBL9481115 0.72 TSHR (0.47)
Chloropicrin SCHEMBL10611964 0.72
SCHEMBL5574571 0.72 TSHR (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010033598-A2 SYSTEM AND METHOD FOR UTILIZING MICROBUBBLES AND LIPOSOMES AS VIRAL SEQUESTERING AGENTS VERUS BIOTECHNOLOGY CORPORATION (US) 2010-03-25 WO claimed
US-20100069814-A1 SYSTEM AND METHOD FOR UTILIZING MICROBUBBLES AND LIPOSOMES AS VIRAL SEQUESTERING AGENTS VERUS BIOTECHNOLOGY CORPORATION 2010-03-18 US claimed
US-7078015-B2 TEMPERATURE ACTIVATED GASEOUS LIPOSOMES; THERAPY DRUG DELIVERY; ACCUMULATING IN CANCER AND DISEASE TISSUE IMARX THERAPEUTICS, INC. (US) 2006-07-18 US claimed
EP-0740528-A4 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP (US) 1998-04-01 EP claimed
US-5733572-A Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles IMARX PHARMACEUTICAL CORP. (US) 1998-03-31 US claimed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 CN claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 EP claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 WO claimed
EP-2766001-B1 BUFFERED OXYGEN THERAPEUTIC NUVOX PHARMA LLC (US) 2024-05-15 EP disclosed
CN-113289034-A Lipid-encapsulated gas microsphere compositions and related methods 蓝瑟斯医学影像公司 2021-08-24 CN disclosed
CN-107206111-B Lipid-encapsulated gas microsphere compositions and related methods 蓝瑟斯医学影像公司 2021-04-27 CN disclosed
US-20180326384-A1 MICROBUBBLES AND THEIR GENERATION UCL BUSINESS PLC (GB) 2018-11-15 US disclosed
EP-3374076-A1 MICROBUBBLES AND THEIR GENERATION UCL BUSINESS PLC (GB) 2018-09-19 EP disclosed
EP-2514387-B1 ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE NAT CT GERIATRICS & GERONTOLOGY (JP) 2018-03-21 EP disclosed
WO-1996039197-A1 STABILIZED COMPOSITIONS OF FLUORINATED AMPHIPHILES AS CONTRAST AGENTS FOR ULTRASOUND IMARX PHARMACEUTICAL CORP. (US) 1996-12-12 WO disclosed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 CN disclosed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 EP disclosed
WO-1995032005-A1 STABILIZED HOMOGENOUS SUSPENSIONS AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX PHARMACEUTICAL CORP. (US) 1995-11-30 WO disclosed
WO-1995032006-A1 GAS FILLED MICROSPHERES AS COMPUTED TOMOGRAPHY CONTRAST AGENTS IMARX, PHARMACEUTICAL CORP. (US) 1995-11-30 WO disclosed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 WO disclosed