Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7228819 | 0.98 | CHRM2 (0.42) | CHRM2CHRM1GRM5FFAR1PIN1 | |
| SCHEMBL7575126 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL27464858 | 0.75 | CHRM2 (0.48) | CHRM2CHRM1GRM5FFAR1PIN1 | |
| SCHEMBL7575152 | 0.74 | CHRM2 (0.39) | CHRM2CHRM1GRM5FFAR1PIN1 | |
| SCHEMBL9906390 | 0.74 | — | — | |
| SCHEMBL81509 | 0.74 | — | — | |
| SCHEMBL2491796 | 0.73 | GRM5 (0.55) | CHRM2CHRM1GRM5FFAR1ADK | |
| Charcoal, Activated SCHEMBL31286311 | 0.71 | GRM5 (0.53) | CHRM2CHRM1GRM5FFAR1ADK | |
| SCHEMBL9067295 | 0.71 | CHRM2 (0.39) | CHRM2CHRM1GRM5FFAR1PIN1 | |
| SCHEMBL1143333 | 0.71 | FFAR1 (0.41) | CHRM2CHRM1GRM5FFAR1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266887-B1 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-08-17 | — | — | EP | disclosed |
| EP-1266887-A2 | Indenoindoline derivatives, their process of preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2002-12-18 | — | — | EP | disclosed |