Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.64 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317764 | 0.92 | MCHR1 (0.85) | MCHR1OPRL1 | |
| SCHEMBL13949523 | 0.91 | MCHR1 (0.84) | MCHR1OPRL1ASIC3 | |
| SCHEMBL6317633 | 0.90 | MCHR1 (0.81) | MCHR1ASIC3 | |
| SCHEMBL6310467 | 0.88 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6223225 | 0.83 | MCHR1 (0.70) | MCHR1OPRL1ASIC3 | |
| SCHEMBL4261878 | 0.81 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL4261887 | 0.81 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL4258680 | 0.80 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL6202831 | 0.78 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6202826 | 0.78 | MCHR1 (1.00) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451156-A4 | 4-AMINOQUINOLINE COMPOUNDS | MERCK & CO INC (US) | 2005-05-25 | — | — | EP | claimed |
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | claimed |
| EP-1451156-A1 | 4-AMINOQUINOLINE COMPOUNDS | Merck & Co., Inc. (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003045920-A1 | 4-AMINOQUINOLINE COMPOUNDS | MERCK & CO., INC. (US) | 2003-06-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | MCHR1 1/4885OPRL1 19/4885ASIC3 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.