Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203445 | 0.84 | TSHR (0.36) | TSHRGAAPOLBTDP1L3MBTL1 | |
| SCHEMBL334176 | 0.79 | TSHR (0.50) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL6202776 | 0.77 | TSHR (0.44) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL30529014 | 0.77 | TSHR (0.48) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL27561555 | 0.77 | TSHR (0.48) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL1014097 | 0.71 | TSHR (0.43) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL1533356 | 0.71 | TSHR (0.48) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL3944331 | 0.71 | TSHR (0.59) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL846984 | 0.71 | EGLN1 (0.45) | TSHRMAPTGAAPOLBTDP1 | |
| SCHEMBL27827275 | 0.71 | CYP1A2 (0.48) | TSHRMAPTGAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | claimed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | claimed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | claimed |
| EP-1501877-A1 | FLUORINATED POLYMERS | Honeywell International Inc. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040126695-A1 | Fluorinated polymers | HONEYWELL INTERNATIONAL, INC. | 2004-07-01 | — | — | US | disclosed |
| WO-2003095505-A1 | FLUORINATED POLYMERS | HONEYWELL INTERNATIONAL INC. (US) | 2003-11-20 | — | — | WO | disclosed |