Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692380 | 0.84 | HTR2A (0.70) | HTR2AHSD17B10IDO1ADRA1ATAAR1 | |
| SCHEMBL3459047 | 0.84 | HTR2A (0.70) | HTR2AHSD17B10IDO1ADRA1ATAAR1 | |
| SCHEMBL8527544 | 0.81 | HTR2A (0.61) | HTR2AHSD17B10IDO1ADRA1ATAAR1 | |
| SCHEMBL3460220 | 0.81 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL1740903 | 0.81 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL31545209 | 0.81 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL1740902 | 0.81 | HTR2A (1.00) | HTR2AIDO1ADRA1ATAAR1 | |
| SCHEMBL4960829 | 0.80 | HTR2A (0.74) | HTR2AHSD17B10IDO1ADRA1ATAAR1 | |
| SCHEMBL6203715 | 0.79 | HTR2A (0.63) | HTR2AHSD17B10IDO1ADRA1ATAAR1 | |
| Hydrochloric Acid SCHEMBL29542459 | 0.79 | HTR2A (0.97) | HTR2AIDO1ADRA1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |