SCHEMBL6203762

SCHEMBL6203762

CN(C(=O)C1(c2cccc3c2C(O)(C(=O)NC2CN4CCC2CC4)c2ccccc2-3)c2ccccc2Oc2ccccc21)[C@H]1CN2CCC1CC2

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 6/20 0.59
CHRM1 P11229 6/20 0.59
CHRM3 P20309 6/20 0.59
UGCG Q16739 2/20 0.37
HTR3A P46098 4/20 0.36
CHRNA7 P36544 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6201266 1.00 CHRM2 (0.59) CHRM2CHRM1CHRM3UGCGHTR3A
SCHEMBL6201270 0.82 CHRM2 (0.68) CHRM2CHRM1CHRM3CHRNA7
SCHEMBL6203759 0.82 CHRM2 (0.68) CHRM2CHRM1CHRM3CHRNA7
SCHEMBL2819764 0.76 CHRM2 (1.00) CHRM2CHRM1CHRM3HTR3ACHRNA7
SCHEMBL2823841 0.76 CHRM2 (1.00) CHRM2CHRM1CHRM3HTR3ACHRNA7
SCHEMBL2820016 0.64 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL2821824 0.64 CHRM2 (1.00) CHRM2CHRM1CHRM3
SCHEMBL2823740 0.62 CHRM3 (0.59) CHRM2CHRM1CHRM3
Bromide SCHEMBL2820158 0.61 CHRM3 (0.58) CHRM2CHRM1CHRM3
SCHEMBL2819759 0.61 CHRM2 (1.00) CHRM2CHRM1CHRM3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005533826-A 2005-11-10 JP claimed
EP-1519933-A1 QUINUCLIDINE AMIDE DERIVATIVES Almirall Prodesfarma AG (CH) 2005-04-06 EP claimed
WO-2004005285-A1 NEW QUINUCLIDINE AMIDE DERIVATIVES ALMIRALL PRODESFARMA AG (CH) 2004-01-15 WO claimed