Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203903 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL6203900 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL4697250 | 0.80 | NR1H2 (0.39) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL4697252 | 0.80 | NR1H2 (0.39) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL15518785 | 0.79 | CHRM2 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL16932134 | 0.79 | CHRM2 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL17972968 | 0.74 | CHRM2 (0.42) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL3617621 | 0.73 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL3617624 | 0.73 | CHRM2 (0.39) | CHRM2CHRM1CHRM3MAPT | |
| SCHEMBL3317786 | 0.70 | CHRM2 (0.36) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1538150-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2005-06-08 | — | — | EP | disclosed |