Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | PRCP | P42785 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28134799 | 1.00 | TSHR (0.60) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL13646900 | 0.84 | TSHR (0.65) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL32689446 | 0.82 | TSHR (0.67) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL5160890 | 0.82 | TSHR (0.67) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL12571279 | 0.79 | TSHR (0.71) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL9637870 | 0.79 | TSHR (0.71) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL3060010 | 0.79 | TSHR (0.71) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL12571281 | 0.79 | TSHR (0.71) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL11104021 | 0.78 | TSHR (0.66) | TSHRNPSR1OPRM1PRCPSLC6A2 | |
| SCHEMBL4022286 | 0.78 | TSHR (0.75) | TSHRNPSR1OPRM1PRCPSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751128-B2 | Process for producing optically active amides | AJINOMOTO KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-5994545-A | TETRAHYDROISOQUINOLINE-3(S)-CARBOXYLIC ACID N-CARBOXY ANHYDRIDE; INTERMEDIATES OF SAQUINAVIR (EP 432694). | AJINOMOTO CO., INC. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0751128-B1 | Process for producing optically active amides | AJINOMOTO KK (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0751128-A1 | Process for producing optically active amides | Ajinomoto Co., Ltd. (JP) | 1997-01-02 | — | — | EP | disclosed |