Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204252 | 1.00 | UTS2R (0.35) | UTS2RCTSLRIPK1CTSKKMT2A | |
| SCHEMBL6204257 | 1.00 | UTS2R (0.35) | UTS2RCTSLRIPK1CTSKKMT2A | |
| SCHEMBL5781254 | 1.00 | UTS2R (0.35) | UTS2RCTSLRIPK1CTSKKMT2A | |
| SCHEMBL5781257 | 1.00 | UTS2R (0.35) | UTS2RCTSLRIPK1CTSKKMT2A | |
| SCHEMBL6204723 | 0.96 | UTS2R (0.36) | UTS2RRIPK1CTSKKMT2AUSP30 | |
| SCHEMBL6204726 | 0.96 | UTS2R (0.36) | UTS2RRIPK1CTSKKMT2AUSP30 | |
| SCHEMBL6204721 | 0.96 | UTS2R (0.36) | UTS2RRIPK1CTSKKMT2AUSP30 | |
| SCHEMBL5783898 | 0.82 | KMT2A (0.39) | UTS2RCTSKKMT2APSEN1PSEN2 | |
| SCHEMBL5783900 | 0.82 | KMT2A (0.39) | UTS2RCTSKKMT2APSEN1PSEN2 | |
| SCHEMBL4748025 | 0.79 | KMT2A (0.36) | UTS2RCTSLCTSKKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020459-B1 | CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-04-06 | — | — | EP | claimed |
| EP-1020459-B1 | CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-04-06 | — | — | EP | disclosed |