Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645766 | 1.00 | DPP4 (0.41) | DPP4ALDH1A1ACELMNA | |
| SCHEMBL646398 | 0.86 | DPP4 (0.40) | DPP4ALDH1A1LMNA | |
| SCHEMBL647239 | 0.84 | DPP4 (0.41) | DPP4ALDH1A1 | |
| SCHEMBL3595601 | 0.84 | ACE (0.32) | ALDH1A1ACE | |
| SCHEMBL6204436 | 0.84 | ACE (0.32) | ALDH1A1ACE | |
| SCHEMBL3599761 | 0.82 | DPP4 (0.40) | DPP4ALDH1A1ACE | |
| SCHEMBL4977537 | 0.81 | DPP4 (0.38) | DPP4ALDH1A1ACE | |
| SCHEMBL6202997 | 0.81 | DPP4 (0.38) | DPP4ALDH1A1ACE | |
| SCHEMBL647621 | 0.81 | DPP4 (0.38) | DPP4ALDH1A1ACE | |
| SCHEMBL6201514 | 0.79 | DPP4 (0.62) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560811-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004026822-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2004-04-01 | — | — | WO | disclosed |