Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204711 | 1.00 | KMT2A (0.41) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL6204713 | 1.00 | KMT2A (0.41) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL5783900 | 0.96 | KMT2A (0.39) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL5783898 | 0.96 | KMT2A (0.39) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL6204721 | 0.82 | UTS2R (0.36) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL6204726 | 0.82 | UTS2R (0.36) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL6204723 | 0.82 | UTS2R (0.36) | KMT2ADPP8DPP9CTSKUTS2R | |
| SCHEMBL2082301 | 0.81 | KMT2A (0.51) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL2082300 | 0.81 | KMT2A (0.51) | KMT2AMETAP2DPP8DPP9MAPK1 | |
| SCHEMBL5781254 | 0.78 | UTS2R (0.35) | KMT2ACTSKUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020459-B1 | CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6184388-B1 | ANTIBACTERIAL AND ANTIMICROBIAL, QUINOLINE ANTIBIOTIC | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6121285-A | 5-AMINO-7-(4-(1-AMINOCYCLOPROPYL-3-FLUORO-1-PYRROLIDINYL)-6 -FLUORO-1-(2-FLUORO-1-CYCLOPROPYL)-1,4-DIHYDRO-8-METHOXY-4-OXOQUINOLINE-3 -CARBOXYLIC ACID, FOR EXAMPLE; ANTIMICROBIAL DRUGS WITH HIGH SAFETY | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-1020459-A1 | CIS-DISUBSTITUTED AMINOCYCLOALKYL-PYRROLIDINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |