Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206065 | 0.79 | TSHR (0.47) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6204948 | 0.79 | ELANE (0.51) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL1145279 | 0.79 | ELANE (0.51) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL8975527 | 0.79 | TSHR (0.56) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6065985 | 0.79 | ELANE (0.47) | ELANECYP1A2MAPTTDP1ALDH1A1 | |
| SCHEMBL6205997 | 0.78 | ELANE (0.43) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6206652 | 0.78 | ELANE (0.43) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6206053 | 0.78 | ELANE (0.43) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6206639 | 0.78 | ELANE (0.43) | ELANECYP1A2MAPTTDP1CES2 | |
| SCHEMBL6204819 | 0.78 | TDP1 (0.44) | ELANECYP1A2MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |