SCHEMBL6205141

SCHEMBL6205141

CC1CCC(C#N)N1C(=O)CNC1(CO)CCCC1

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647944 1.00 DPP4 (0.83) DPP4
SCHEMBL2742688 0.91 DPP4 (1.00) DPP4
SCHEMBL14838005 0.91 DPP4 (1.00) DPP4
SCHEMBL19416678 0.91 DPP4 (1.00) DPP4
Hydrochloric Acid SCHEMBL29386862 0.91 DPP4 (1.00) DPP4
SCHEMBL1377808 0.85 DPP4 (0.83) DPP4
SCHEMBL647582 0.85 DPP4 (0.83) DPP4
SCHEMBL15627964 0.85 DPP4 (0.88) DPP4
SCHEMBL10064422 0.85 DPP4 (0.83) DPP4
SCHEMBL14218339 0.85 DPP4 (0.83) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560811-A2 PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) Abbott Laboratories (US) 2005-08-10 EP disclosed
WO-2004026822-A2 PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) ABBOTT LABORATORIES (US) 2004-04-01 WO disclosed