Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 15/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.83 |
| ▸ | NOS1 | P29475 | 4/20 | 0.76 |
| ▸ | NOS2 | P35228 | 4/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996670 | 0.91 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| Fumaric Acid SCHEMBL5996536 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| Fumaric Acid SCHEMBL5996532 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5996571 | 0.85 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5996287 | 0.85 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL4482541 | 0.84 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5805973 | 0.84 | SLC6A2 (0.86) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| SCHEMBL5994994 | 0.82 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3NOS1NOS2 | |
| Fumaric Acid SCHEMBL5997504 | 0.82 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL5997512 | 0.82 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569905-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004052858-A2 | INHIBITORS OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |