Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 5/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461214 | 0.96 | CHRNA7 (0.36) | CHRNA7WNT1DYRK1AGSK3BALDH1A1 | |
| SCHEMBL4509727 | 0.82 | GSK3B (0.53) | DYRK1AGSK3BCDK1CDK2NAMPT | |
| SCHEMBL4509800 | 0.78 | GSK3B (0.59) | GSK3BALDH1A1L3MBTL1CDK1CDK2 | |
| SCHEMBL4497527 | 0.78 | KDM4E (0.50) | GSK3BALDH1A1L3MBTL1CDK1CDK2 | |
| SCHEMBL4494753 | 0.74 | GSK3B (0.64) | WNT1DYRK1AGSK3BCDK1CDK2 | |
| SCHEMBL4500932 | 0.73 | GSK3B (0.62) | GSK3BCDK1CDK2HSD17B10HTR3A | |
| SCHEMBL6207558 | 0.72 | GSK3B (0.58) | GSK3BCDK1CDK2HSD17B10HTR3A | |
| SCHEMBL4492707 | 0.71 | GSK3B (0.69) | GSK3BCDK1CDK2 | |
| SCHEMBL2337608 | 0.71 | GSK3B (0.49) | GSK3BCDK1CDK2HSD17B10HTR3A | |
| SCHEMBL1461200 | 0.71 | GSK3B (0.61) | GSK3BCDK1CDK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537087-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022544-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2004-03-18 | — | — | WO | disclosed |